Initially, naltrexone was used to address opioid overdose, with typical dosages ranging from 50 to 100 milligrams. However, a significant shift occurred in the 1990s when healthcare professionals began prescribing naltrexone in markedly reduced doses, typically ranging from 1.5 to 4.5 milligrams. This shift aimed to modulate the immune system and manage various inflammatory and neurological conditions.
The utilization of LDN has yielded promising results in a diverse range of health conditions, including but not limited to:
- Chronic Fatigue Syndrome and Fibromyalgia
- Gastrointestinal disorders like Irritable Bowel Syndrome, Crohn’s Disease, and Ulcerative Colitis
- Autoimmune thyroid disorders such as
- Hashimoto’s and Graves’ Disease
- Dermatological conditions like Psoriasis and Eczema
- Different forms of Arthritis
- Various other inflammatory conditions
- Mood disorders like Depression
- Restless Leg Syndrome
- Systemic Lupus Erythematosus
- HIV/AIDS
- Chronic pain disorders
- Autism Spectrum Disorder
In general, LDN is well-tolerated, and adverse effects are typically minimal. Some individuals may experience initial vivid dreams, while others infrequently report transient headaches or mild body aches.